Treatment of chronic rhinosinusitis using erythromycin phonophoresis.

[a***@yahoo.fr]

Physiother Theory Pract. 2012 Aug 14. [Epub ahead of print]
Treatment of chronic rhinosinusitis using erythromycin phonophoresis.
Ansari NN, Fathali M, Naghdi S, Bartley J, Rastak MS.
Source
Associate Professor, Department of Physiotherapy, School of Rehabilitation , Tehran University of Medical Sciences , Tehran , Iran.

Abstract
Bacterial biofilms have been implicated in many chronic infective diseases, including chronic rhinosinusitis (CRS). Therapeutic ultrasound enhances the breakdown of bacterial biofilms and is clinically effective in CRS treatment, while phonophoresis has also been utilized for antibiotic delivery through the skin. The objective of this case report is to describe the results of a novel treatment, erythromycin phonophoresis, in a woman with CRS. A 31-year-old woman with a 7-month history of CRS refractory to conventional medical management was treated with erythromycin phonophoresis to both maxillary sinuses. Individual sinus symptom severity was assessed and sinus CT scans were obtained both pretreatment and posttreatment. After treatment, the total sinusitis symptom score improved from 12 to 0 and the CT scan showed almost complete disease resolution. At 5-month follow-up, the patient reported sustained improvement. Erythromycin phonophoresis has potential as an effective treatment for CRS.

[truehawk]

This is an important post,
I remember several other studies showing using ultrasound to break up the biofilm so that antibiotics can get to the bacteria work.
This reminds me that radio ablation which has been found to have the lowest relapse rate, but for reasons one can conjecture, radio-ablation has never been included in the standard treatment guidelines, and insurance usually won't pay for it.

Post by a***@yahoo.fr
Physiother Theory Pract. 2012 Aug 14. [Epub ahead of print]
Treatment of chronic rhinosinusitis using erythromycin phonophoresis.
Ansari NN, Fathali M, Naghdi S, Bartley J, Rastak MS.
Source
Associate Professor, Department of Physiotherapy, School of Rehabilitation , Tehran University of Medical Sciences , Tehran , Iran.
Abstract
Bacterial biofilms have been implicated in many chronic infective diseases, including chronic rhinosinusitis (CRS). Therapeutic ultrasound enhances the breakdown of bacterial biofilms and is clinically effective in CRS treatment, while phonophoresis has also been utilized for antibiotic delivery through the skin. The objective of this case report is to describe the results of a novel treatment, erythromycin phonophoresis, in a woman with CRS. A 31-year-old woman with a 7-month history of CRS refractory to conventional medical management was treated with erythromycin phonophoresis to both maxillary sinuses. Individual sinus symptom severity was assessed and sinus CT scans were obtained both pretreatment and posttreatment. After treatment, the total sinusitis symptom score improved from 12 to 0 and the CT scan showed almost complete disease resolution. At 5-month follow-up, the patient reported sustained improvement. Erythromycin phonophoresis has potential as an effective treatment for CRS.
Physiother Theory Pract. 2012 Aug 14. [Epub ahead of print]
Treatment of chronic rhinosinusitis using erythromycin phonophoresis.
Ansari NN, Fathali M, Naghdi S, Bartley J, Rastak MS.
Source
Associate Professor, Department of Physiotherapy, School of Rehabilitation , Tehran University of Medical Sciences , Tehran , Iran.
Abstract
Bacterial biofilms have been implicated in many chronic infective diseases, including chronic rhinosinusitis (CRS). Therapeutic ultrasound enhances the breakdown of bacterial biofilms and is clinically effective in CRS treatment, while phonophoresis has also been utilized for antibiotic delivery through the skin. The objective of this case report is to describe the results of a novel treatment, erythromycin phonophoresis, in a woman with CRS. A 31-year-old woman with a 7-month history of CRS refractory to conventional medical management was treated with erythromycin phonophoresis to both maxillary sinuses. Individual sinus symptom severity was assessed and sinus CT scans were obtained both pretreatment and posttreatment. After treatment, the total sinusitis symptom score improved from 12 to 0 and the CT scan showed almost complete disease resolution. At 5-month follow-up, the patient reported sustained improvement. Erythromycin phonophoresis has potential as an effective treatment for CRS.